A Case of Von Hippel-Lindau Disease with Multi-Organ Involvement

Abstract

1. Abstract
Von Hippel–Lindau (VHL) is an autosomal dominant disease with multi-organ involvement in familial neoplasm. Genetic aberrations of the tumor suppressor gene VHL cause it. Based on the reports in VHL, the most common initial presentation tumors are hemangioblastoma in the CNS and retina.